Potential role of metalloproteinase inhibitors from radiation‑sterilized amnion dressings in the healing of venous leg ulcers.

@article{Litwiniuk2012PotentialRO,
  title={Potential role of metalloproteinase inhibitors from radiation‑sterilized amnion dressings in the healing of venous leg ulcers.},
  author={Małgorzata Litwiniuk and Barbara Bikowska and Justyna Niderla-Bielińska and Jarosław J{\'o}źwiak and Artur Kamiński and Piotr Skopinski and Tomasz Grzela},
  journal={Molecular medicine reports},
  year={2012},
  volume={6 4},
  pages={
          723-8
        }
}
Chronic wounds are a significant socio-economic problem, thus, the improvement of the effectiveness of their treatment is an important objective for public health strategies. The predominant stage of the chronic wound is the inflammatory reaction which is associated with the damage of tissues, possibly due to the excessive secretion and activation of matrix metalloproteinases (MMPs). Several reports have suggested that amnion dressing inhibits tissue destruction and accelerates wound healing… CONTINUE READING

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