Potential role for direct gene transfer in the enhancement of fracture healing.

@article{Goldstein1998PotentialRF,
  title={Potential role for direct gene transfer in the enhancement of fracture healing.},
  author={Steven A. N. Goldstein and Jeffrey Bonadio},
  journal={Clinical orthopaedics and related research},
  year={1998},
  volume={355 Suppl},
  pages={S154-62}
}
This paper describes the use of localized transient gene therapy for the augmentation of fracture healing. It introduces a method involving the delivery of plasmid deoxyribonucleic acid via a three dimensional matrix into a wound, with in vivo transfection of wound repair cells resulting, their subsequent expression of factors that condition the wound site… CONTINUE READING