Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza.

@article{Chen2012PotentialRF,
  title={Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza.},
  author={Wilbur H Chen and Franklin R Toapanta and Kari Ann Shirey and Lei Zhang and Angeliki Giannelou and Carly A Page and Matthew B. Frieman and Stefanie N. Vogel and Alan S. Cross},
  journal={Immunology letters},
  year={2012},
  volume={141 2},
  pages={227-34}
}
PURPOSE Secondary bacterial infections are a common complication of influenza. Innate immune host defenses appear to be impaired following influenza, leading to susceptibility to subsequent bacterial infections. Alternatively activated macrophages (AAM) in the lungs may play a critical role in eliciting the hypersusceptibility to secondary bacterial pneumonia. METHODS C57BL6 mice were challenged with sublethal doses of the mouse-adapted A/PR/8/34 (PR8) influenza virus or saline and allowed to… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Benchto-bedside review: bacterial pneumonia with influenza – pathogenesis and clinical implications

  • KF van der Sluijs, PT van der, R Lutter, NP Juffermans, MJ. Schultz
  • Crit Care 2010;14:219
  • 2010
2 Excerpts

Similar Papers

Loading similar papers…