Potential pro-inflammatory effects of soluble E-selectin upon neutrophil function.

  title={Potential pro-inflammatory effects of soluble E-selectin upon neutrophil function.},
  author={M.-H. Ruchaud-Sparagano and Ellen M. Drost and Seamas Donnelly and Michael I Bird and Christopher Haslett and Ian Dransfield},
  journal={European journal of immunology},
  volume={28 1},
Appropriate recruitment of neutrophils to sites of infection or tissue injury is a key event in the inflammatory response. A number of studies have shown the critical role of selectins in tethering and rolling of neutrophils on vascular endothelium, as well as a more complex regulatory role, since they have the potential to alter leukocyte recruitment by triggering beta2 integrin-mediated adhesion. In this study, we report that in contrast to patients "at risk" of developing acute respiratory… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…