Potential precursors to neuromedin N in the cat and their processing by pepsin.

  title={Potential precursors to neuromedin N in the cat and their processing by pepsin.},
  author={R. Carraway and S. P. Mitra},
  volume={120 5},
  • R. Carraway, S. P. Mitra
  • Published 1987
  • Biology, Medicine
  • Endocrinology
  • Acidic (0.1 N HCl) extracts of feline brain and ileal mucosa were found to contain a number of basic proteins which yielded immunoreactive neuromedin N (NMN) when treated with hog pepsin. These proteins substrates were separated using Sephadex G-25, Sephadex G-75, and reverse phase HPLC. In a calibrated sodium dodecyl sulfate-polyacrylamide gel electrophoresis system, the major substrates from cat ileum gave mol wt of about 15K and 20K. Minor bands of substrates, possible aggregates, were… CONTINUE READING
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