Potential precursors to neuromedin N in the cat and their processing by pepsin.

@article{Carraway1987PotentialPT,
  title={Potential precursors to neuromedin N in the cat and their processing by pepsin.},
  author={R. Carraway and S. P. Mitra},
  journal={Endocrinology},
  year={1987},
  volume={120 5},
  pages={
          2101-7
        }
}
  • R. Carraway, S. P. Mitra
  • Published 1987
  • Biology, Medicine
  • Endocrinology
    • Acidic (0.1 N HCl) extracts of feline brain and ileal mucosa were found to contain a number of basic proteins which yielded immunoreactive neuromedin N (NMN) when treated with hog pepsin. These proteins substrates were separated using Sephadex G-25, Sephadex G-75, and reverse phase HPLC. In a calibrated sodium dodecyl sulfate-polyacrylamide gel electrophoresis system, the major substrates from cat ileum gave mol wt of about 15K and 20K. Minor bands of substrates, possible aggregates, were… CONTINUE READING
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    12 Citations
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    Precursor forms of neurotensin (NT) in cat: processing with pepsin yields NT-(3–13) and NT-(4–13)
    • 21
    Differential processing of the neurotensin/neuromedin N precursor in the mouse
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    Generation of Met-enkephalin Arg6Phe7 immunoreactivity by proteolytic cleavage of mammalian plasma precursors by pepsin.
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    The use of radioimmunoassay to compare the tissue and subcellular distributions of neurotensin and neuromedin N in the cat.
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    Processing of the Precursors to Neurotensin and Other Bioactive Peptides by Cathepsin E (*)
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    Presence of neurotensin and neuromedin-N within a common precursor from a human pancreatic neuroendocrine tumor.
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    Enhanced expression of neurotensin/neuromedin N mRNA and products of NT/NMN precursor processing in neonatal rats
    • 11
    Posttranslational Processing of the Neurotensin/Neuromedin‐N Precursor
    • 55
    Neuromedin-N is not released with neurotensin from rat ileum.
    • 28
    The characterization and regional distribution of neuromedin N-like immunoreactivity in rat brain using a highly sensitive and specific radioimmunoassay. Comparison with the distribution of neurotensin
    • 25

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