Potential pleiotropic effects of Mpdz on vulnerability to seizures.

Abstract

We previously mapped quantitative trait loci (QTL) responsible for approximately 26% of the genetic variance in acute alcohol and barbiturate (i.e., pentobarbital) withdrawal convulsion liability to a < 1 cM (1.8 Mb) interval of mouse chromosome 4. To date, Mpdz, which encodes the multiple PSD95/DLG/ZO-1 (PDZ) domain protein (MPDZ), is the only gene within… (More)

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Cite this paper

@article{Fehr2004PotentialPE, title={Potential pleiotropic effects of Mpdz on vulnerability to seizures.}, author={Carla Fehr and Renee L. Shirley and Pamela Metten and A E K Kosobud and J. K. Belknap and J. C. Crabbe and Kari J. Buck}, journal={Genes, brain, and behavior}, year={2004}, volume={3 1}, pages={8-19} }