Potential of various drugs to inhibit nucleoside uptake in rat syncytiotrophoblast cell line, TR-TBT 18d-1.

@article{Chishu2008PotentialOV,
  title={Potential of various drugs to inhibit nucleoside uptake in rat syncytiotrophoblast cell line, TR-TBT 18d-1.},
  author={Takuya Chishu and Yoshimichi Sai and Tomohiro Nishimura and Kae Sato and Noriko Kose and Emi Nakashima},
  journal={Placenta},
  year={2008},
  volume={29 5},
  pages={461-7}
}
The placenta requires nucleosides as nutrients for fetal growth, so it is important to examine potential interactions between placental transports of nucleosides and drugs to ensure the safety of pharmacotherapy during pregnancy. The purposes of this study are to clarify the uptake mechanisms of nucleosides from the maternal side of the syncytiotrophoblast and to investigate the inhibitory effect of various drugs on nucleoside uptake, using the rat syncytiotrophoblast cell line TR-TBT 18d-1… CONTINUE READING
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