Potential of human umbilical cord matrix and rabbit bone marrow-derived mesenchymal stem cells in repair of surgically incised rabbit external anal sphincter.

@article{AghaeeAfshar2009PotentialOH,
  title={Potential of human umbilical cord matrix and rabbit bone marrow-derived mesenchymal stem cells in repair of surgically incised rabbit external anal sphincter.},
  author={Mahmoud Aghaee-Afshar and Mohammad Rezazadehkermani and Alireza Asadi and Reza Malekpour-afshar and Armita Shahesmaeili and Seyed Noureddin Nematollahi-Mahani},
  journal={Diseases of the colon and rectum},
  year={2009},
  volume={52 10},
  pages={1753-61}
}
PURPOSE Anal sphincter defects and fecal incontinence are complicated surgical problems. We investigated the ability of human umbilical cord matrix (hUCM) and rabbit bone marrow (rBM) stem cells to improve anal sphincter incontinence due to induced sphincter defects without surgical repair. METHODS We harvested hUCM cells from human Wharton's jelly and rBM stem cells from rabbit femurs and tibias. To induce sphincter defects, we made an incision in the external anal sphincter. Rabbits were… CONTINUE READING

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