Potential nonhormonal therapeutics for medical treatment of leiomyomas.

  title={Potential nonhormonal therapeutics for medical treatment of leiomyomas.},
  author={Steven L. Young and Ayman A Al-Hendy and John A. Copland},
  journal={Seminars in reproductive medicine},
  volume={22 2},
Uterine leiomyomas are a common disorder resulting in significant morbidity for women and substantial economic impact on the health care system. Current therapies include conservative surgery, hysterectomy, and hormonal therapy. Conservative surgical therapy often fails because of recurrence, and hysterectomy dramatically limits reproductive options. Radiologic therapies are associated with considerable risk of morbidity and mortality and are not likely to be compatible with reproduction… CONTINUE READING