Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia.

@article{John2003PotentialMO,
  title={Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia.},
  author={Stefan John and Roland E Schmieder},
  journal={Current hypertension reports},
  year={2003},
  volume={5 3},
  pages={199-207}
}
This review focuses on the role of impaired endothelial function for the development of atherosclerosis in human arterial hypertension and hypercholesterolemia in vivo. Potential mechanisms underlying impaired endothelial function and decreased bioavailability of nitric oxide under these clinical conditions are discussed. It further addresses therapeutic strategies aimed at improving the bioavailability of nitric oxide in these patients. The overall conclusion is that the bioavailability of… CONTINUE READING

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