Potential mechanism for Calvados-related oesophageal cancer.

  title={Potential mechanism for Calvados-related oesophageal cancer.},
  author={Klas Linderborg and Jean Pierre Joly and J P Visap{\"a}{\"a} and Mikko P Salaspuro},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  volume={46 2},
The old Normandian habit of consumption of hot Calvados is associated with an increased risk of oesophageal cancer compared to other alcoholic beverages. The role of alcohol consumption in the risk of oesophageal cancer is well established. The first metabolite of alcohol, acetaldehyde is a potential local carcinogen in humans. Accordingly, different acetaldehyde concentrations in different beverages could account for some of the variations in cancer risk with regard to the type of alcoholic… CONTINUE READING
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