Potential manipulation of endothelial progenitor cells in diabetes and its complications.

@article{Fadini2010PotentialMO,
  title={Potential manipulation of endothelial progenitor cells in diabetes and its complications.},
  author={Gian Paolo Fadini and Angelo Avogaro},
  journal={Diabetes, obesity & metabolism},
  year={2010},
  volume={12 7},
  pages={570-83}
}
Diabetes mellitus increases cardiovascular risk through its negative impact on vascular endothelium. Although glucotoxicity and lipotoxicity account for endothelial cell damage, endothelial repair is also affected by diabetes. Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial homoeostasis and in the process of new vessel formation. For these reasons, EPCs are thought to have a protective impact within the cardiovascular system. In addition, EPCs appear to… CONTINUE READING