Potential involvement of leptin in carcinogenesis of hepatocellular carcinoma.

@article{Wang2004PotentialIO,
  title={Potential involvement of leptin in carcinogenesis of hepatocellular carcinoma.},
  author={Xiu-Jie Wang and Shu-lan Yuan and Qing Lu and Yan-rong Lu and Jie Zhang and Yan Liu and Wen-dong Wang},
  journal={World journal of gastroenterology},
  year={2004},
  volume={10 17},
  pages={2478-81}
}
AIM To investigate the potential involvement of leptin in carcinogenesis of hepatocellular carcinoma (HCC) and to elucidate the etiology, carcinogenesis and progress of HCC. METHODS Expressions of Ob gene product, leptin and its receptor, Ob-R were investigated in 36 cases of HCC specimens and corresponding adjacent non-tumorous liver tissues with immunohistochemical staining. The effect of leptin on proliferation of Chang liver cell line and liver cancer cell line SMMC-7721 was studied with… CONTINUE READING

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