Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation.

@article{Deperthes1996PotentialIO,
  title={Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation.},
  author={David Deperthes and Gilles Frenette and Mich{\`e}le Brillard-Bourdet and Luc Bourgeois and Francis L Gauthier and Roland R. Tremblay and Johanne Dub{\'e}},
  journal={Journal of andrology},
  year={1996},
  volume={17 6},
  pages={659-65}
}
We have recently demonstrated in liquefied human seminal plasma the presence of the novel kallikrein hK2 in association with protein C inhibitor (PCI) as a 75-kDa complex. In the present study, we showed that hK2, immediately after ejaculation, was recovered only in its free form but complex formation with PCI occurred rapidly thereafter and was completed within 10 minutes. That reaction required an enzymatically active kallikrein. In order to determine the patterns of hydrolysis of major… CONTINUE READING

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References

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Showing 1-10 of 20 references

Prostate - specific antigen releases a kininlike substance on proteolysis of seminal vesicle fluid that stimulates smooth muscle contraction

  • Fichtner J. Graves HCB, K Thatcher, C Yemoto, LM Shortliffe
  • J Urol
  • 1996

Isolation of prostatic kallikrein hK 2 , also known as hGK1 , in human seminal plasma

  • D Deperthes, C ChapdelaineP.TremblayRR.Brunet, J Berton, C Lazure
  • Biochim Biophys Acw
  • 1995
3 Excerpts

Some sensitive methods

  • hibitors. Eur J Biochem, PL 194755-763.Coleman, EN LathamHGJr.Shaw
  • 1990

proteins and their reactions during gelation and liquefaction of human semen

  • RS McGee, JC Herr
  • J Clin Invest
  • 1988
1 Excerpt

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