Potential interaction between valproic acid and doripenem.


A potential interaction between valproate (VPA) and doripenem leading to decreased valproic acid concentrations in two patients is described. In the first patient case, a 54-year-old female presented to the emergency department following a seizure episode after stopping her medications a few days prior. She was given a 1500 mg (23 mg/kg) intravenous (IV… (More)


Cite this paper

@article{Hellwig2011PotentialIB, title={Potential interaction between valproic acid and doripenem.}, author={Thaddaus R Hellwig and Mallory L Onisk and Bret A Chapman}, journal={Current drug safety}, year={2011}, volume={6 1}, pages={54-8} }