Potential hazards to embryo implantation: A human endometrial in vitro model to identify unwanted antigestagenic actions of chemicals.

@article{Fischer2012PotentialHT,
  title={Potential hazards to embryo implantation: A human endometrial in vitro model to identify unwanted antigestagenic actions of chemicals.},
  author={L. Fischer and W. R. Deppert and D. Pfeifer and S. Stanzel and M. Weimer and A. Hanjalic-Beck and A. Stein and Markus Stra{\ss}er and H. P. Zahradnik and W. Sch{\"a}fer},
  journal={Toxicology and applied pharmacology},
  year={2012},
  volume={260 3},
  pages={
          232-40
        }
}
  • L. Fischer, W. R. Deppert, +7 authors W. Schäfer
  • Published 2012
  • Chemistry, Medicine
  • Toxicology and applied pharmacology
  • Embryo implantation is a crucial step in human reproduction and depends on the timely development of a receptive endometrium. The human endometrium is unique among adult tissues due to its dynamic alterations during each menstrual cycle. It hosts the implantation process which is governed by progesterone, whereas 17β-estradiol regulates the preceding proliferation of the endometrium. The receptors for both steroids are targets for drugs and endocrine disrupting chemicals. Chemicals with… CONTINUE READING
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