Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.

@article{Kastury1996PotentialGT,
  title={Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.},
  author={Kumar Kastury and Raffaele Baffa and Teresa Druck and Masataka Ohta and Maria Grazia Cotticelli and Hiroshi Inoue and Massimo Negrini and M Rugge and Dongqing Huang and Carlo M. Croce and Juan A Palazzo and Kay F Huebner},
  journal={Cancer research},
  year={1996},
  volume={56 5},
  pages={978-83}
}
A number of DNA fragments, identified by representational difference analysis, which were homozygously deleted in various cancer cell lines were previously mapped to human chromosomal arms. One of these, BE758-6, which was homozygously deleted in a number of colon carcinoma cell lines, had been mapped to chromosome region 3p. We have further localized the probe to 3p14.2, approximately 350kbp telomeric to the 3p14.2 break of the t(3;8) hereditary renal cell carcinoma chromosome translocation… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Evaluation of FHIT gene alterations in ovarian cancer.

British Journal of Cancer • 1998
View 7 Excerpts
Highly Influenced

Genetics/genomics/proteomics of gastric adenocarcinoma.

Gastroenterology clinics of North America • 2013
View 1 Excerpt

Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus • 2012

Aberrant FHIT expression is linked to bladder carcinogenesis and apoptosis.

Asian Pacific journal of cancer prevention : APJCP • 2011
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Comparative genomic analysis of tumors : Detection of DNA losses and amplification

N. A. Lisitsyn, N. M. Liiitsina, +6 authors M. H. Wigler
Proc . Nail . Acad . Sci . USA • 1995

Dinucleotide repeats flanking the renal cell carcinoma breakpoint at 3 p 1 ' I . 2

J. Roche, E. Whisenant, +3 authors H. Drabkin
Cancer Genet . Cytogenet . • 1995

Inactivation of the type II TGF( 3 receptor in colon cancer cells with microsatellite instability

S. Markowitz, J. Wang, +7 authors J. K. V. Wilson
Science ( Washington DC ) • 1995

Receptor proteintyrosine phospha tase g is a candidate tumor suppressor gene at human chromosome region 3 p 21

S. LaForgia, B. Morse, +13 authors K. Huebner
Genomics • 1995

Structure ofthe human receptortyrosine phosphatase gamma gene ( PTPRG ) and relation to the familial RCC t ( 3 ; 8 ) chromosome translocation

K. Kastuiy, M. Ohta, +5 authors K. Huebner
Cancer Res . • 1995

Characterization and chromosomal assignment of yeast artificial chromosomes containing human 3 p 13p 21specific sequence tagged sites

S. C. Michaelis, W. Bardenheuer, +16 authors J. SchOtte
Genes Chromosomes & Cancer • 1994

Similar Papers

Loading similar papers…