Potential forensic application of DNA methylation profiling to body fluid identification

@article{Lee2011PotentialFA,
  title={Potential forensic application of DNA methylation profiling to body fluid identification},
  author={H. Lee and M. J. Park and Ajin Choi and Ja Hyun An and W. Yang and Kyoung-Jin Shin},
  journal={International Journal of Legal Medicine},
  year={2011},
  volume={126},
  pages={55-62}
}
DNA analysis of various body fluid stains at crime scenes facilitates the identification of individuals but does not currently determine the type and origin of the biological material. Recent advances in whole genome epigenetic analysis indicate that chromosome pieces called tDMRs (tissue-specific differentially methylated regions) show different DNA methylation profiles according to the type of cell or tissue. We examined the potential of tissue-specific differential DNA methylation for body… Expand
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  • 64
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5
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References

SHOWING 1-10 OF 36 REFERENCES
Multiplex mRNA profiling for the identification of body fluids.
  • 281
mRNA Profiling for Body Fluid Identification by Multiplex Quantitative RT‐PCR *
  • 180
Quantitative analysis of human tissue-specific differences in methylation.
  • 38
New markers for old stains: stable mRNA markers for blood and saliva identification from up to 16-year-old stains
  • 120
  • PDF
Analysis of tissue-specific differentially methylated regions (TDMs) in humans.
  • 79
Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression.
  • Fei Song, J. F. Smith, +4 authors W. Held
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2005
  • 347
  • PDF
...
1
2
3
4
...