Potential for use of pulse wave analysis in determining the interaction between sildenafil and glyceryl trinitrate.

@article{ORourke2002PotentialFU,
  title={Potential for use of pulse wave analysis in determining the interaction between sildenafil and glyceryl trinitrate.},
  author={Michael F. O'Rourke and Wilmer W. Nichols},
  journal={Clinical cardiology},
  year={2002},
  volume={25 6},
  pages={295-9}
}
BACKGROUND The early part of the central aortic pressure pulse, with amplitude (PI - Pd), is generated by left ventricular ejection, while the latter part (or augmented pressure), with amplitude (Ps - Pi), is generated by the reflected wave arriving during systole. The effects of arterial vasodilator agents, especially nitrates, on central aortic systolic blood pressure are grossly underestimated by sphygmomanometric measurements of brachial artery pressure. HYPOTHESIS The objective of this… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…