Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience

@inproceedings{Lin2016PotentialEO,
  title={Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience},
  author={Chien-Ming Lin and Hueng-Chuen Fan and T Chao and Der-Ming Chu and Chi-Chieh Lai and Chih-Chien Wang and Shyi-Jou Chen},
  booktitle={BMC Pediatrics},
  year={2016}
}
BackgroundChildren with longstanding use of antiepileptic drugs (AEDs) are susceptible to developing low bone mineral density and an increased fracture risk. However, the literature regarding the effects of AEDs on growth in epileptic children is limited. The aim of this study was to investigate the potential effects of valproate (VPA) and/or oxcarbazepine (OXC) therapy on growth velocity and bone metabolism.MethodsSeventy-three ambulatory children (40 boys and 33 girls) with epilepsy, aged… CONTINUE READING
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