Potential diagnostic biomarkers: differential expression of LMP2/β1i and cyclin B1 in human uterine leiomyosarcoma.

@article{Hayashi2014PotentialDB,
  title={Potential diagnostic biomarkers: differential expression of LMP2/β1i and cyclin B1 in human uterine leiomyosarcoma.},
  author={Takuma Hayashi and Akiko Horiuchi and Kenji Sano and Nobuyoshi Hiraoka and Tomoyuki Ichimura and Tamotsu Sudo and Osamu Ishiko and Nobuo Yaegashi and Hiroyuki Aburatani and Ikuo Konishi},
  journal={Tumori},
  year={2014},
  volume={100 4},
  pages={99e-106e}
}
AIMS AND BACKGROUND Whilst most uterine smooth muscle neoplasms are benign, uterine leiomyosarcoma (Ut-LMS) is extremely malignant with a high incidence of metastasis and recurrence. Gynecological tumors are often associated with female hormone secretion, but no strong link has been detected between human Ut-LMS and the hormonal environment. In fact, the risk factors for Ut-LMS are poorly understood. In addition, no diagnostic biomarkers for differentiating between leiomyoma, a benign tumor… CONTINUE READING