Potential cancer chemopreventive agents from Arbutus unedo.

  title={Potential cancer chemopreventive agents from Arbutus unedo.},
  author={Esperanza J Carcache-Blanco and Muriel Cuendet and Eun Jung Park and Bao-Ning Su and N. R. Farnsworth and John M Pezzuto and A Douglas Kinghorn},
  journal={Natural product research},
  volume={20 4},
A phytochemical study of the petroleum ether and ethyl acetate extracts of the entire plant of Arbutus unedo led to the isolation of a new sterol, 7beta-hydroxystigmast-4-en-3-one (1), and nine known compounds of the flavan, steroid, and terpenoid types. The structure of 1 was determined by spectroscopic data interpretation in combination with molecular modeling calculations. The absolute stereochemistry of C-7 was assigned as S for compound 1 based on the obtained CD spectral data. Activity in… CONTINUE READING
Highly Cited
This paper has 18 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-7 of 7 extracted citations

Antioxidant and antiproliferative properties of strawberry tree tissues

L. Tavaresa, S. Fortalezasa, +4 authors Claudia Nunes Duarte dos Santosa
View 3 Excerpts
Highly Influenced