Potential benefits of mindfulness-based interventions in mild cognitive impairment and Alzheimer's disease: An interdisciplinary perspective

  title={Potential benefits of mindfulness-based interventions in mild cognitive impairment and Alzheimer's disease: An interdisciplinary perspective},
  author={Eddy Larouche and Carol Hudon and Sonia Goulet},
  journal={Behavioural Brain Research},
The purpose of this paper is to identify to what extent the development of Alzheimer’s disease can be delayed or prevented through the use of mindfulness-based interventions. Alzheimer’s disease (AD)
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Non-pharmacological Approaches Based on Mind-Body Medicine to Enhancement of Cognitive and Brain Reserve in Humans
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Mindfulness Awareness Practice (MAP) to Prevent Dementia in Older Adults with Mild Cognitive Impairment: Protocol of a Randomized Controlled Trial and Implementation Outcomes
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  • Medicine, Psychology
    International journal of environmental research and public health
  • 2021
This is the first randomized controlled trial to systematically investigate the effects of a mindfulness intervention in improving cognitive functions and various biomarkers in community-dwelling older adults diagnosed with mild cognitive impairment (MCI).
Into the Moment: Does Mindfulness Affect Biological Pathways in Multiple Sclerosis?
It is proposed to include immunological and/or neuroimaging biomarkers as standard outcome measures in future research dedicated to mindfulness and MS to help explain the clinical improvements seen in fatigue and depression.
A Systematic Review of Mindfulness-Based Interventions for Patients with Mild Cognitive Impairment or Dementia and Caregivers
Results indicated that the magnitude of post-treatment effects of MBIs are in the medium to large range for psychosocial outcomes, and in the small to medium range for cognitive functioning; however, treatment effects on dementia biomarkers were mixed, ranging from small to large, depending on the outcome measure.
Mindfulness and psychoeducation to manage stress in amnestic mild cognitive impairment: A pilot study
This pilot study supports the potential of MBI and PBI to reduce stress at the physiological and psychological level, respectively, and increase coping strategies in older adults at risk for AD.


Meditation for Adults with Mild Cognitive Impairment: A Pilot Randomized Trial
Mindfulness Based Stress Reduction (MBSR), a standardized mindfulness meditation/yoga intervention, may decrease stress/cortisol, improve well-being, and increase hippocampal gray matter density in healthy adults.
Neuropsychiatric Manifestations in Mild Cognitive Impairment: A Systematic Review of the Literature
The behavioral changes observed in MCI are similar to those of AD and may help identify the subgroup of MCI patients with prodromal AD, and large prospective longitudinal studies would greatly contribute to the understanding of the epidemiology, diagnostic and prognostic value of the neuropsychiatric features inMCI.
Psychological distress and risk for dementia
Results presented in this review show that psychological distress and depressive, anxious, and apathetic symptoms can be present in MCI and may predict progression to dementia.
Proneness to psychological distress is associated with risk of Alzheimer’s disease
Proneness to experience psychological distress is a risk factor for Alzheimer’s disease, an effect independent of AD pathologic markers such as cortical plaques and tangles.
Vulnerability to stress, anxiety, and development of dementia in old age.
Neuroticism's association with late-life dementia mainly reflects vulnerability to stress and anxiety and their correlation with decline in the ability to process and retain new information.
Late-life depression, mild cognitive impairment, and dementia: possible continuum?
  • F. Panza, V. Frisardi, V. Solfrizzi
  • Psychology, Medicine
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2010
Clinical and epidemiologic research has focused on the identification of risk factors that may be modified in predementia syndromes, at a preclinical and early clinical stage of dementing disorders,