Corpus ID: 36752639

Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients with diabetic foot.

@article{Karadurmu2010PotentialBO,
  title={Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients with diabetic foot.},
  author={Nuri Karadurmuş and Mustafa Şahin and Canturk Tasci and Ilkin Naharci and Cengiz Ozturk and Savas Ilbasmis and Zeki Dulkadir and Ahmet Şen and Kenan Sağlam},
  journal={Endokrynologia Polska},
  year={2010},
  volume={61 3},
  pages={
          275-9
        }
}
INTRODUCTION The aim of this study was to investigate the effects of hyperbaric oxygen therapy (HBOT) on glycaemic control, atherosclerosis, inflammatory markers, and other clinical and laboratory parameters in patients undergoing systemic HBOT for diabetic foot ulcerations. MATERIAL AND METHODS Twenty-eight patients with Wagner grade 2-4 diabetic foot ulcerations were included. All patients were given 100% oxygen at 2.4 absolute atmosphere (ATA) for about 105 minutes, five times a week for a… Expand
Blood glucose and lipid profile in patients with diabetic foot ulcer that underwent hyperbaric oxygen therapy
TLDR
There is no significant effect of HBOT to decrease blood sugar, but the significant increase of lipid profile may be caused by the reaction of lipid peroxidation. Expand
A Pilot Study of Short-Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine in Patients with Diabetic Foot Ulcer Wagner 3-4
TLDR
The use of short-duration HBOT on DFU reduces HbA1c levels, leukocyte count, and serum creatinine levels better than standard therapy alone and this protocol would save time and effort in future HBOT implementation. Expand
Hyperbaric Oxygen Therapy Dampens Inflammatory Cytokine Production and Does Not Worsen the Cardiac Function and Oxidative State of Diabetic Rats
TLDR
The results suggest that HBOT does not increase long-term oxidative stress, and, similar to training, the TBARS products, nitrotyrosine formation and poly(ADP-ribosyl)ation may be eased as a result of hyperoxia. Expand
The Effects of Hyperbaric Oxygen Therapy on Blood Glucose Levels and Lipid Profile in Diabetes Mellitus Patients
TLDR
There is a significant decrease in blood glucose level and lipid profile (total cholesterol, and triglycerides) after hyperbaric oxygen therapy. Expand
Role of Hyperbaric Oxygen Therapy on Microvascular Diabetic Complications and Metabolic Profile among Patients with Type 2 Diabetes Mellitus
TLDR
Findings from animal (rat) studies indicate that the periodic HBOT exposure limits some of the damage associated with the chronic high blood glucose levels, particularly those mediated through oxidative pathways. Expand
Hyperbaric Oxygen Therapy to Reduce Blood Glucose Level on Patients Diabetes Mellitus
TLDR
There was the influence of hyperbaric oxygen therapy with decreasing blood glucose level, and there are improvements pancreatic beta cell function and increased tissue sensitivity to insulin due to increased oxidative phosphorylation process in pancreatic Beta-cell mitochondria to increase ATP production in Pancic beta cells. Expand
Hyperbaric Oxygen Therapy Improves Glucose Homeostasis in Type 2 Diabetes Patients: A Likely Involvement of the Carotid Bodies.
TLDR
It is suggested that hyperbaric oxygen therapy (HBOT) could be used as a therapeutic intervention for type 2 diabetes and show that HBOT ameliorates glucose tolerance in diabetic patients. Expand
Hyperbaric Oxygen Therapy and Vascular Complications in Diabetes Mellitus
TLDR
Hyperbaric oxygen therapy affects molecules involved in the regulation of nitric oxide synthesis and in that way exerts anti-inflammatory and angiogenic effects in patients with DM, and the recent literature related to the effects of HBOT is explored. Expand
Tissue-specific role of Nrf2 in the treatment of diabetic foot ulcers during hyperbaric oxygen therapy.
TLDR
The findings of the present study suggest that HBO therapy promotes wound healing by increasing oxygen supply and distribution to damaged tissues, stimulating angiogenesis, decreasing inflammation, and increasing the nitrite levels. Expand
Adjunctive Hyperbaric Oxygen Therapy for Healing of Chronic Diabetic Foot Ulcers: A Randomized Controlled Trial
TLDR
Adjunctive HBOT improved wound healing in persons with DFU and reduced the risk of amputation of the affected limb, and at least 20 HBOT sessions are required to be effective. Expand
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