Potential benefits of estrogens and progestogens on breast cancer.

@article{Schneider1998PotentialBO,
  title={Potential benefits of estrogens and progestogens on breast cancer.},
  author={Hermann P. G. Schneider and C. Jackisch},
  journal={International journal of fertility and women's medicine},
  year={1998},
  volume={43 6},
  pages={
          278-85
        }
}
The mammary gland seems to be the only organ that is not fully developed at birth. Estrogens stimulate breast tissue via estrogen receptors (ERs). In the mammary gland, ER-mediated mechanisms have been shown to regulate: various growth factors, such as TGF-alpha and TGF-beta; enzymes, such as cathepsin D and plasminogen-activator; proto-oncogenes, such as c-fos, c-myc and HER-2/neu; cyclines and other regulatory substances that provide signaling systems for cell division and differentiation… CONTINUE READING

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