Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz

@article{Dabaghzadeh2012PotentialBO,
  title={Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz},
  author={Fatemeh Dabaghzadeh and Hossein Khalili and Padideh Ghaeli and Simin Dashti-Khavidaki},
  journal={Expert Opinion on Pharmacotherapy},
  year={2012},
  volume={13},
  pages={2613 - 2624}
}
Introduction: More than 50% of HIV-positive patients experience neuropsychiatric adverse reactions following efavirenz therapy. Discontinuation of efavirenz due to its neuropsychiatric side effects has been reported in 2 – 13% of patients. Dizziness, headache, nightmares, abnormal dreams, mild cognitive difficulty, sleep disturbance (somnolence and insomnia), impaired concentration, depression, hallucination, delusion, paranoia, anxiety, agitation, aggressive behavior, mania, emotional… 
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RE: Severe mental illness at ART initiation is associated with worse retention in care among HIV‐infected Ugandan adults by JM Nachega et al. (2013), TMIH 18, pp 53–57
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