Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz

@article{Dabaghzadeh2012PotentialBO,
  title={Potential benefits of cyproheptadine in HIV-positive patients under treatment with antiretroviral drugs including efavirenz},
  author={Fatemeh Dabaghzadeh and H. Khalili and Padideh Ghaeli and S. Dashti-Khavidaki},
  journal={Expert Opinion on Pharmacotherapy},
  year={2012},
  volume={13},
  pages={2613 - 2624}
}
Introduction: More than 50% of HIV-positive patients experience neuropsychiatric adverse reactions following efavirenz therapy. Discontinuation of efavirenz due to its neuropsychiatric side effects has been reported in 2 – 13% of patients. Dizziness, headache, nightmares, abnormal dreams, mild cognitive difficulty, sleep disturbance (somnolence and insomnia), impaired concentration, depression, hallucination, delusion, paranoia, anxiety, agitation, aggressive behavior, mania, emotional… Expand
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References

SHOWING 1-10 OF 63 REFERENCES
A Systematic Review of the Psychiatric Side-Effects of Efavirenz
  • 123
Neuropsychiatric side effects of efavirenz therapy
  • 88
Long-Term Safety and Efficacy of NNRTI Within the Central Nervous System
  • 23
Long-Term Neuropsychiatric Disorders on Efavirenz-Based Approaches: Quality of Life, Psychologic Issues, and Adherence
  • 172
Stepped-Dose Versus Full-Dose Efavirenz for HIV Infection and Neuropsychiatric Adverse Events
  • 48
  • PDF
Central Nervous System Adverse Effects with Efavirenz: Case Report and Review
  • 66
Preliminary Data of a Prospective Study on Neuropsychiatric Side Effects After Initiation of Efavirenz
  • 71
Neurologic and Psychiatric Complications of Antiretroviral Agents
  • 83
  • PDF
Treatment of Depression With Cyproheptadine
  • 11
Effects of the HIV treatment drugs nevirapine and efavirenz on brain creatine kinase activity
  • 41
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