Corpus ID: 7775884

Potential antitumor agents XIX [1]. Synthesis and antitumor activity of tricyclic compounds related to lotifazole.

@article{Andreani1992PotentialAA,
  title={Potential antitumor agents XIX [1]. Synthesis and antitumor activity of tricyclic compounds related to lotifazole.},
  author={A. Andreani and M. Rambaldi and A. Locatelli and A. Fraccari and R. Bossa and I. Galatulas},
  journal={Pharmaceutica acta Helvetiae},
  year={1992},
  volume={67 8},
  pages={
          234-6
        }
}
  • A. Andreani, M. Rambaldi, +3 authors I. Galatulas
  • Published 1992
  • Chemistry, Medicine
  • Pharmaceutica acta Helvetiae
  • The synthesis of phenothiazine and anthraquinone derivatives, bearing at least one fragment present in lotifazole, is reported. Some of the new compounds showed antitumor activity in vitro (P388 leukemia cells) and in vivo (Ehrlich ascites tumor cells in mice). 
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