Potential and limitations of regulatory T-cell therapy in solid organ transplantation.

Abstract

Over the past few years, the therapeutic potential of Treg has been highlighted in the field of autoimmune diseases and after allogeneic transplantation. The first hurdle for the therapeutic use of Treg is their insufficient numbers in non-manipulated individuals, in particular when facing strong immune activation and expanding effector cells, such as in… (More)
DOI: 10.1586/1744666X.2014.943191

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