Potential Role of Caffeine in the Treatment of Parkinson’s Disease
@article{Roshan2016PotentialRO, title={Potential Role of Caffeine in the Treatment of Parkinson’s Disease}, author={Mohsin H K Roshan and A. Tambo and N. Pace}, journal={The Open Neurology Journal}, year={2016}, volume={10}, pages={42 - 58} }
Parkinson’s disease [PD] is the second most common neurodegenerative disorder after Alzheimer’s disease, affecting 1% of the population over the age of 55. The underlying neuropathology seen in PD is characterised by progressive loss of dopaminergic neurons in the substantia nigra pars compacta with the presence of Lewy bodies. The Lewy bodies are composed of aggregates of α-synuclein. The motor manifestations of PD include a resting tremor, bradykinesia, and muscle rigidity. Currently there is… CONTINUE READING
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