Potential Mechanisms of Action of Lithium in Bipolar Disorder

  title={Potential Mechanisms of Action of Lithium in Bipolar Disorder},
  author={G. Malhi and M. Tanious and P. Das and C. Coulston and M. Berk},
  journal={CNS Drugs},
  • G. Malhi, M. Tanious, +2 authors M. Berk
  • Published 2013
  • Medicine
  • CNS Drugs
  • Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in this role. [...] Key Method A comprehensive literature search of databases including MEDLINE, EMBASE and PsycINFO was conducted using relevant keywords and the findings from the literature were then reviewed and synthesized. Numerous studies report that lithium is effective in the treatment of acute mania and for the long-term…Expand Abstract
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