Potential 166Ho radiopharmaceuticals for endovascular radionuclide therapy. II. Preparation and evaluation of 166Ho-DTPA.

@article{Majali2001Potential1R,
  title={Potential 166Ho radiopharmaceuticals for endovascular radionuclide therapy. II. Preparation and evaluation of 166Ho-DTPA.},
  author={Mythili A Majali and Sanjay Kumar Saxena and Shripad Pandurang Joshi and P M Raghavan Unni and Natesan Ramamoorthy},
  journal={Nuclear medicine communications},
  year={2001},
  volume={22 1},
  pages={
          97-103
        }
}
166Ho, with its favourable radiation characteristics of t(1/2) 26.8 h and Ebeta 1.85 and 1.75 MeV, is proposed as a suitable choice for the endovascular radionuclide therapy (EVRT) technique of liquid filled, low pressure balloon angioplasty. 166Ho was produced by the (n,gamma) reaction on a natural Ho2O3 target. The specific activity obtained was approximately 100 mCi x mg(-1) when irradiated at a flux of 2 x 10(13) n x cm(-2) s(-1) for approximately 7 days, and the possible contaminant 166Ho… CONTINUE READING
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