Potent rifamycin-sparing regimen cures guinea pig tuberculosis as rapidly as the standard regimen.

Abstract

Strategies involving new drug combinations, as well as new uses of existing drugs, are urgently needed to reduce the time required to cure patients with drug-sensitive or multidrug-resistant (MDR) tuberculosis (TB). We compared the sterilizing activity of the standard first-line antitubercular regimen, rifampin-isoniazid-pyrazinamide (RHZ), with that of the… (More)
DOI: 10.1128/AAC.00761-13

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