Potent neutralization of staphylococcal enterotoxin B by synergistic action of chimeric antibodies.

Abstract

Staphylococcal enterotoxin B (SEB), a shock-inducing exotoxin synthesized by Staphylococcus aureus, is an important cause of food poisoning and is a class B bioterrorism agent. SEB mediates antigen-independent activation of a major subset of the T-cell population by cross-linking T-cell receptors (TCRs) with class II major histocompatibility complex (MHC-II… (More)
DOI: 10.1128/IAI.01121-09

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