Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetes.

@article{Bellin2012PotentII,
  title={Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetes.},
  author={Melena D Bellin and Franca Benedicty Barton and Andrew Heitman and James V Harmon and Raja Kandaswamy and A. N. Balamurugan and David E. R. Sutherland and Rodolfo Alejandro and Bernhard J. Hering},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2012},
  volume={12 6},
  pages={1576-83}
}
The seemingly inexorable decline in insulin independence after islet transplant alone (ITA) has raised concern about its clinical utility. We hypothesized that induction immunosuppression therapy determines durability of insulin independence. We analyzed the proportion of insulin-independent patients following final islet infusion in four groups of ITA recipients according to induction immunotherapy: University of Minnesota recipients given FcR nonbinding anti-CD3 antibody alone or T cell… CONTINUE READING
88 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 88 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Beta-cell secretory capacity after human islet transplantation by the CIT07 versus Edmonton protocol: Preliminary results

  • MR Rickels, AJ Chiou, C Fuller
  • Am J Transplant
  • 2011
2 Excerpts

Similar Papers

Loading similar papers…