Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer.


Following targeted gene virotherapy, the suppression of tumorigenicity 13 (ST13) gene was inserted into the double-regulated oncolytic adenovirus SG500 to ensure more safety and potent antitumor activity against colorectal cancer in vitro and in vivo. We generated the ST13-expressing oncolytic adenovirus SG500-ST13, with which colorectal carcinoma cell… (More)
DOI: 10.1111/j.1349-7006.2009.01110.x


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