Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. The Swiss HIV Cohort Study.

@article{Vernazza2000PotentAT,
  title={Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. The Swiss HIV Cohort Study.},
  author={Pietro Vernazza and Luigi Troiani and Markus Flepp and Richard W. Cone and J L Schock and Felix Maximilian Roth and Katia Boggian and Myron S. Cohen and Susan A. Fiscus and Joseph J Eron},
  journal={AIDS},
  year={2000},
  volume={14 2},
  pages={117-21}
}
OBJECTIVE The amount of HIV in semen likely influences infectiousness. Antiretroviral therapy decreases HIV-RNA in semen, but data on HIV concentrations in semen in a large cohort of men with suppressed HIV-RNA in blood is unavailable. METHODS Male patients with a treatment-induced reduction of HIV-RNA load in plasma below 400 copies/ml were asked to donate a semen and blood sample. Blood and seminal plasma were tested for the presence of HIV-RNA by the NucliSens method (detection limit 400… CONTINUE READING