Potent anorexic-like effects of RDS-127 (2-di-n-propylamino-4,7-dimethoxyindane) in the rat: A comparison with other dopamine-receptor agonists

@article{Arneric1982PotentAE,
  title={Potent anorexic-like effects of RDS-127 (2-di-n-propylamino-4,7-dimethoxyindane) in the rat: A comparison with other dopamine-receptor agonists},
  author={S. Arneric and A. Roetker and J. Long},
  journal={Neuropharmacology},
  year={1982},
  volume={21},
  pages={885-890}
}
  • S. Arneric, A. Roetker, J. Long
  • Published 1982
  • Chemistry, Medicine
  • Neuropharmacology
  • Modification of food intake and motor activity was investigated following administration of amphetamine (AMP), apomorphine (APO) and three novel 2-aminoindanes (2-AI): 2-di-n-propylaminoindane (JPC-60-36), 2-di-n-propylamino-5,6-dimethoxyindane (JPC-211) and 2-di-n-propylamine-4,7-dimethoxyindane (RDS-127). These compounds demonstrated dose- and time-related inhibition of food intake in male rats which were habituated to eating 4 hr each day. The ranked potencies were as follows: RDS-127… CONTINUE READING
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