Potent and broad-spectrum antimicrobial activity of CXCL14 suggests an immediate role in skin infections.

@article{Maerki2009PotentAB,
  title={Potent and broad-spectrum antimicrobial activity of CXCL14 suggests an immediate role in skin infections.},
  author={Christa Maerki and Simone Meuter and Mark Liebi and Kathrin S M{\"u}hlemann and Mitchell Jay Frederick and Nikhil Yawalkar and Bernhard Moser and Marlene Wolf},
  journal={Journal of immunology},
  year={2009},
  volume={182 1},
  pages={
          507-14
        }
}
The skin is constantly exposed to commensal microflora and pathogenic microbes. The stratum corneum of the outermost skin layer employs distinct tools such as harsh growth conditions and numerous antimicrobial peptides (AMPs) to discriminate between beneficial cutaneous microflora and harmful bacteria. How the skin deals with microbes that have gained access to the live part of the skin as a result of microinjuries is ill defined. In this study, we report that the chemokine CXCL14 is a broad… CONTINUE READING
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