Potency of progestogens used in hormonal therapy: Toward understanding differential actions

@article{Hapgood2014PotencyOP,
  title={Potency of progestogens used in hormonal therapy: Toward understanding differential actions},
  author={J. Hapgood and D. Africander and R. Louw and R. Ray and J. Rohwer},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={2014},
  volume={142},
  pages={39-47}
}
Progestogens are widely used in contraception and in hormone therapy. Biochemical and molecular biological evidence suggests that progestogens differ widely in their affinities and transcriptional effects via different steroid receptors, and hence cannot be considered as a single class of compounds. Consistent with these observations, recent clinical evidence suggests that, despite their similar progestogenic actions, these differences underlie different side-effect profiles for cardiovascular… Expand
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