Potency and selectivity indices of acetone leaf extracts of nine selected South African trees against six opportunistic Enterobacteriaceae isolates from commercial chicken eggs

  title={Potency and selectivity indices of acetone leaf extracts of nine selected South African trees against six opportunistic Enterobacteriaceae isolates from commercial chicken eggs},
  author={Ishaku Leo Elisha and Alexander Ray Jambalang and Francien Susanna Botha and Elna Maria Buys and Lyndy Joy McGaw and Jacobus Nicolaas Eloff},
  journal={BMC Complementary and Alternative Medicine},
BackgroundThe rise in antimicrobial resistance in a plethora of nosocomial and opportunistic bacterial pathogens often isolated from commercial eggs, poses a serious public health concern. The existence of these contaminants may also serve as a drawback in the current efforts of improving the well-being of immunocompromised patients. The aim of this study was to determine the efficacy of plant extracts that had good activity on Escherichia coli in previous word on pathogens isolated from eggs… 
Antibacterial, antiquorum sensing, antibiofilm activities and chemical profiling of selected South African medicinal plants against multi-drug resistant bacteria
The biological assays validated the tested plant extracts as having antibacterial and antipathogenic potentials that could be used against multidrug resistant bacteria.
Flavonoids isolated from the South African weed Chromolaena odorata (Asteraceae) have pharmacological activity against uropathogens
This is the first time these compounds have been isolated from the South African weed C. odorata and tested for antimicrobial, anti-biofilm, metabolic inhibition and anti-adhesion activities, indicating that the compounds were rather toxic to the microbial strains and not to the human and animal cells.
Potency and selectivity indices of Myristica fragrans Houtt. mace chloroform extract against non-clinical and clinical human pathogens
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Rec reproducibility of previously reported activities from plants’ extracts is a multi-factorial aspect and collective approaches are necessary in addressing the highlighted challenges.
A comprehensive study of the potential phytomedicinal use and toxicity of invasive Tithonia species in South Africa
Both species may be further developed as a source of antimicrobials for the treatment of infections caused by opportunistic pathogens and may also serve as alternatives to highly exploited plant species with the same medicinal properties.
Antimicrobial Activity, Antioxidant Potential, Cytotoxicity and Phytochemical Profiling of Four Plants Locally Used against Skin Diseases
The current findings provide some degree of scientific evidence supporting the use of these four plants in folk medicine, however, the plants with high cytotoxicity need to be used with caution.
Scientific validation of the antimicrobial and antiproliferative potential of Clerodendrum serratum (L.) Moon, its phytoconstituents and their biosafety by acute oral toxicity study
The screening of aqueous extract of Clerodendrum serratum revealed its broad-spectrum antimicrobial potential against Gram positive, Gram negative bacteria, and yeast, and the overall study justified the medicinal importance of this plant.
Scientific validation of the antimicrobial and antiproliferative potential of Berberis aristata DC root bark, its phytoconstituents and their biosafety
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Five Ochna species have high antibacterial activity and more than ten antibacterial compounds
Based on the bioautography results, the two most active species, O. pretoriensis and O. pulchra, contained at least 10 antibacterial compounds with similar R f values, and Variation in the chemical composition of the species may have some taxonomic value.
The efficacy and safety of nine South African medicinal plants in controlling Bacillus anthracis Sterne vaccine strain
The crude acetone extracts of the selected plant species had promising antibacterial activity against Bacillus anthracis and Hypericum roeperianum could be useful to protect animals based on its high total activity and selectivity index.
Which tree orders in southern Africa have the highest antimicrobial activity and selectivity against bacterial and fungal pathogens of animals?
  • E. Pauw, J. Eloff
  • Biology, Medicine
    BMC Complementary and Alternative Medicine
  • 2014
Against all classes of microorganisms, the four orders containing species with the highest average antimicrobial activities also contained several species with low activities against different pathogens and vice versa.
Studies on Antimicrobial and Immunomodulatory Effects of Hot Aqueous Extract of Acacia nilotica L. Leaves against Common Veterinary Pathogens
Investigation of the antibacterial, antifungal, antiviral, and immunomodulatory potential of hot aqueous extract of Acacia nilotica leaves finds both proliferative and inhibitory effects on the rat splenocytes and IL-10 release depending on the dose.
Phytochemistry and Preliminary Assessment of the Antibacterial Activity of Chloroform Extract of Amburana cearensis (Allemão) A.C. Sm. against Klebsiella pneumoniae Carbapenemase-Producing Strains
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Use of natural antimicrobials to increase antibiotic susceptibility of drug resistant bacteria.
Activity of Some Iranian Plant Extracts against Multi-Drug Resistant Human Pathogens Isolated from Urinary Tract Infections
This investigation showed that the mixes of P. harmal and M. comminus L. extracts have a potent antimicrobial activity against some Gram-positive pathogenic and Gram-negative bacteria.
Some South African Rubiaceae Tree Leaf Extracts Have Antimycobacterial Activity Against Pathogenic and Non‐pathogenic Mycobacterium Species
Leaf extracts of 15 tree species from the Rubiaceae family were screened for antimycobacterial activity against pathogenic M. tuberculosis and non‐pathogenic Mycobacterium smegmatis, Myc Cobacterium aurum and MycOBacterium bovis BCG using a twofold serial microdilution assay, and bioautography indicated at least 40 different antimyCobacterial compounds in the extracts.
Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia.