Potassium-selective microelectrode revealed difference in threshold potassium concentration for cortical spreading depression in female and male rat brain.


It has been found with potassium-selective microelectrodes that the threshold extracellular concentration of potassium [K(+)](e) for eliciting fast spreading depression from the site of administration 1.5mm away is 80% lower in the rat female cortex (8.0 ± 0.6 mM) than in the male cortex (14.4 ± 0.4mM). The rate of the first slow phase of [K(+)](e) rise… (More)
DOI: 10.1016/j.brainres.2010.11.018


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