Potassium inhibition of transforming protein P85gag-mos and reversal of the transformed phenotype in 6m2 cells.

@article{Lai1988PotassiumIO,
  title={Potassium inhibition of transforming protein P85gag-mos and reversal of the transformed phenotype in 6m2 cells.},
  author={Calvin Lai and Gary E. Gallick and Steven A. Maxwell and Bill R. Brinkley and Frederick F. Becker},
  journal={Journal of cellular physiology},
  year={1988},
  volume={134 3},
  pages={445-52}
}
K+ at high concentrations (52-72 mM hypertonic KCl) has been reported to induce reverse transformation in the 6m2 cell, which is a clone of normal rat kidney cells (NRK) infected with a temperature-sensitive transformation virus. When exposed to high K+, 6m2 cells grown at the permissive temperature (33 degrees C) exhibit normal morphology and reduced soft… CONTINUE READING