Potassium induced relaxation of vascular smooth muscle: A possible mechanism of exercise hyperaemia

  title={Potassium induced relaxation of vascular smooth muscle: A possible mechanism of exercise hyperaemia},
  author={Giancarlo Biamino and H J Wessel},
  journal={Pfl{\"u}gers Archiv},
The relaxing effect of small increases in extracellular K+-concentration ([K+]0) on helical strip preparations of the rat aorta, activated by 2 μg norepinephrine/l, was investigated by simultaneously recording mechanical and extracellular mass electrical activity, the latter from two different points. The results of 148 separate experiments show that increases in [K+]0 in a range between 2.7 and 12.7 mM produce decreases in tension corresponding to vasodilation in vivo. The relaxing effect of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 30 references

Uber Beziehungen zwisehen Tonus und elektrischer Aktivitat dcr glatten Gef~l~musknlatur

  • G. Biamino, P. Kruekenberg, WesseI, . H.J
  • Pflfigers Arch. 315, 212--231
  • 1970
Highly Influential
3 Excerpts

The effects of changes in the ionic environment on venous smooth muscle distribution of sodium and potassium

  • Wahlstr5m, 3.
  • Aeta physiol, scand. 82, 382--392
  • 1971
1 Excerpt

Contributions of the sodium pump and ionic gradients to the membrane potential of a molluscan neurone

  • A.L.F. Gorman, Marmor, F. 1.
  • J. Physiol. (Lond.) 210, 897--917
  • 1970
1 Excerpt

Spontanrhythmik und contractiler Tonus der isolierten Rattenaorta in Abh~ngigkeit yon der extracelluli~ren Noradrenalin-, K § und Ca++-Konzentratio~

  • G. Biamino, H. L. Thron
  • Pflfigers Arch. 805, 361--381
  • 1969
1 Excerpt

Similar Papers

Loading similar papers…