Potassium induced relaxation of vascular smooth muscle: A possible mechanism of exercise hyperaemia

@article{Biamino1973PotassiumIR,
  title={Potassium induced relaxation of vascular smooth muscle: A possible mechanism of exercise hyperaemia},
  author={Giancarlo Biamino and H J Wessel},
  journal={Pfl{\"u}gers Archiv},
  year={1973},
  volume={343},
  pages={95-106}
}
The relaxing effect of small increases in extracellular K+-concentration ([K+]0) on helical strip preparations of the rat aorta, activated by 2 μg norepinephrine/l, was investigated by simultaneously recording mechanical and extracellular mass electrical activity, the latter from two different points. The results of 148 separate experiments show that increases in [K+]0 in a range between 2.7 and 12.7 mM produce decreases in tension corresponding to vasodilation in vivo. The relaxing effect of… CONTINUE READING

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