Potassium evoked in vivo release of substance P in rat caudate nucleus measured using a new technique of brain dialysis and an improved substance P-radioimmunoassay.

Abstract

Semipermeable tubules were implanted in rat caudate nucleus in vivo. The tubules were perfused with artificial cerebrospinal fluid and the dialysates collected in fractions which were analysed for substance P content by a sensitive radioimmunoassay (detection limit: 0.1 fmol SP per sample). During controls periods no or comparatively small amounts of SP… (More)

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Cite this paper

@article{Brodin1983PotassiumEI, title={Potassium evoked in vivo release of substance P in rat caudate nucleus measured using a new technique of brain dialysis and an improved substance P-radioimmunoassay.}, author={Ernst Brodin and Nils Lindefors and Urban Ungerstedt}, journal={Acta physiologica Scandinavica. Supplementum}, year={1983}, volume={515}, pages={17-20} }