Potassium cotransport at the rat choroid plexus.

  title={Potassium cotransport at the rat choroid plexus.},
  author={Richard F. Keep and Jianming Xiang and Anthony Betz},
  journal={The American journal of physiology},
  volume={267 6 Pt 1},
The choroid plexuses are involved in cerebrospinal fluid (CSF) secretion and CSF K homeostasis. We examined K transport mechanisms present in the isolated rat choroid plexus that may be involved in these functions, predominantly using 86Rb as a marker for K. The study demonstrates that there are two primary uptake mechanisms. Ouabain-sensitive Na-K-adenosinetriphosphatase and bumetanide-sensitive cotransport, probably of the Na-K-2Cl form, account for 48 and 46% of uptake, respectively. Efflux… CONTINUE READING

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