Potassium channels in pulmonary arterial hypertension.

  title={Potassium channels in pulmonary arterial hypertension.},
  author={Olivier Boucherat and Sophie Chabot and Fabrice Antigny and Fr{\'e}d{\'e}ric Perros and Steeve Provencher and S{\'e}bastien Bonnet},
  journal={The European respiratory journal},
  volume={46 4},
Pulmonary arterial hypertension (PAH) is a devastating cardiopulmonary disorder with various origins. All forms of PAH share a common pulmonary arteriopathy characterised by vasoconstriction, remodelling of the pre-capillary pulmonary vessel wall, and in situ thrombosis. Although the pathogenesis of PAH is recognised as a complex and multifactorial process, there is growing evidence that potassium channels dysfunction in pulmonary artery smooth muscle cells is a hallmark of PAH. Besides… CONTINUE READING
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