Potassium channel opener pinacidil induces relaxation of the isolated human radial artery.

@article{Stojnic2007PotassiumCO,
  title={Potassium channel opener pinacidil induces relaxation of the isolated human radial artery.},
  author={Natasa Stojnic and Ljiljana Gojkovic-Bukarica and Miodrag S Peri{\'c} and Leposava Grbovi{\'c} and Aleksandar R Le{\vs}i{\'c} and Marko Ž Bumba{\vs}irevi{\'c} and Helmut Heinle},
  journal={Journal of pharmacological sciences},
  year={2007},
  volume={104 2},
  pages={122-9}
}
Taking into consideration that the search for drugs capable of modifying blood flow through human radial artery (RA) is warranted, the present study was designed to examine the vasodilatatory effects of the potassium channel opener, pinacidil on the RA and to define the contribution of different K+ -channel subtypes in the endothelium-independent pinacidil action on this blood vessel. Pinacidil relaxed the RA rings with endothelium and without endothelium with comparable potency. N-nitro-L… CONTINUE READING