Potassium balance during treatment of diabetic ketoacidosis with special reference to the use of bicarbonate.

@article{Soler1972PotassiumBD,
  title={Potassium balance during treatment of diabetic ketoacidosis with special reference to the use of bicarbonate.},
  author={Norman G. Soler and Mary A. Bennett and K. Dixon and MuirisX. Fitzgerald and J. M. Malins},
  journal={Lancet},
  year={1972},
  volume={2 7779},
  pages={
          665-7
        }
}
Sodium bicarbonate therapy in severe diabetic ketoacidosis.
Electrocardiogram as a Guide to Potassium Replacement in Diabetic Ketoacidosis
TLDR
The electrocardiogram is a useful guide to potassium replacement in diabetic ketoacidosis and should be an important objective of treatment in the successful management of this diabetic emergency.
Metabolic effects of bicarbonate in the treatment of diabetic ketoacidosis.
TLDR
There is no metabolic indication for the use of intravenous bicarbonate in the treatment of diabetic ketoacidosis and no difference in the rate of fall of blood glucose concentration was found.
Pathogenesis, diagnosis and treatment of diabetic ketoacidosis.
  • M. Kogut
  • Medicine
    Current problems in pediatrics
  • 1976
Does bicarbonate therapy improve the management of severe diabetic ketoacidosis?
TLDR
Data from the literature and this study are not in favor of the use of bicarbonate in the treatment of diabetic ketoacidosis with pH values between 6.90 and 7.10.
Use of base in the treatment of severe acidemic states.
  • J. Kraut, I. Kurtz
  • Medicine, Biology
    American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2001
TLDR
The potential value of base therapy in the treatment of severe acidemia remains an important issue, and further studies are required to determine which patients should be administered base therapy and what base should be used.
Bicarbonate in diabetic ketoacidosis - a systematic review
TLDR
The evidence to date does not justify the administration of bicarbonate for the emergent treatment of DKA, especially in the pediatric population, in view of possible clinical harm and lack of sustained benefits.
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References

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Potassium deficiency occurring during the treatment of diabetic acidosis.
  • J. Holler
  • Medicine
    Journal of the American Medical Association
  • 1946
TLDR
The case of J. W., a white girl aged 18, single, admitted to the Strong Memorial hospital on Jan. 24, 1946, had been known to be diabetic for three years, treated with 35 units of protamine zinc insulin a day.
Diabetic acidosis with initial hypokalemia. Therapeutic implications.
TLDR
Initial hypokalemia in diabetic ketoacidosis is an uncommon finding, implying severe total body potassium depletion in excess of that usually encountered, and potassium replacement should commence early in treatment, after the presence of adequate urine output has been established.
Diabetic Ketoacidosis During the Influenza Epidemic
TLDR
During eight weeks of a recent influenza epidemic 29 patients with ketoacidosis were admitted to the General Hospital, Birmingham, this was an exceptionally large number of cases and hypokalaemia was present on admission in several instances and caused respiratory failure and death in three patients.
ACID-BASE BALANCE IN CEREBROSPINAL FLUID.
TLDR
The cerebrospinal fluid pH depends almost entirely on its carbon dioxide-bicarbonate ratio (CO2/HCO-3) and contains so little protein that its buffering capacity resembles a 20 millimolar (mM) bicarbonates solution.
Cerebral edema with irreversible coma in severe diabetic ketoacidosis.
THE number of deaths from severe diabetic acidosis has been significantly reduced in recent years with adequate insulin treatment and a better understanding of fluid and electrolyte balance.