Postural and Anticonvulsant Effects of Inhibition of the Rat Subthalamic Nucleus

@article{Dybdal2000PosturalAA,
  title={Postural and Anticonvulsant Effects of Inhibition of the Rat Subthalamic Nucleus},
  author={David Dybdal and Karen Gale},
  journal={The Journal of Neuroscience},
  year={2000},
  volume={20},
  pages={6728 - 6733}
}
  • David Dybdal, Karen Gale
  • Published 2000
  • Biology, Medicine
  • The Journal of Neuroscience
  • The subthalamic nucleus (STN) plays a crucial role as a regulator of basal ganglia outflow by providing excitatory glutamatergic input into the two output nuclei of the basal ganglia, substantia nigra pars reticulata (SNpr), and entopeduncular nucleus. This study examined the effects of suppressing activity in the STN of the awake, behaving rat. Specifically, we evaluated the effects of unilateral and bilateral focal inhibition of STN on posture, locomotion, and susceptibility to limbic motor… CONTINUE READING

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