Posttransplantation lymphoproliferative disorders frequently contain type A and not type B Epstein-Barr virus.

@article{Frank1995PosttransplantationLD,
  title={Posttransplantation lymphoproliferative disorders frequently contain type A and not type B Epstein-Barr virus.},
  author={Dale Frank and Ethel Cesarman and Yi Fang Liu and R E Michler and Daniel M. Knowles},
  journal={Blood},
  year={1995},
  volume={85 5},
  pages={1396-403}
}
Two families of Epstein-Barr virus (EBV), type A and type B, have been defined on the basis of sequence divergence in the EBNA-2 gene. Type A EBV immortalizes B cells more efficiently in vitro and infects immunocompetent individuals more commonly than type B EBV. However, increased rates of infection by type B EBV are seen in immunocompromised hosts and in many lymphoid neoplasms associated with immunocompromise. The posttransplantation lymphoproliferative disorders (PT-LPDs) are a… CONTINUE READING